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Genome Center for Alzheimer’s Disease (GCAD)

GCAD is funded by the NIA to harmonize relevant whole genome/exome sequencing data for the identification of risk/causative/protective genetic variants and eventual therapeutic targets for AD. GCAD is responsible for generating project-level sequence datasets, implementing quality control (QC) on them, and making them publicly available for research. Going forward, GCAD will extend data production to generate genotype calling for structural variants (SVs) and process/harmonize functional genomics data to extend AD genomic analyses.