The Alzheimer’s Disease Sequencing Project (ADSP) is performing cutting edge analyses of genome sequencing and related health data across global populations to understand the genetic architecture of Alzheimer’s Disease and Related Dementias.

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For ADSP Members

Visit your customized dashboard to view your ADSP information.

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For Researchers

Learn more ADSP research, data, and resources, and ways to get involved.

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For the Public

See how ADSP is helping to shape the science of Alzheimer’s Disease research.

News and Publications

Agentic AI and Robotics: AD/ADRD and Beyond workshop graphic
Register now for the Agentic AI and Robotics: Accelerating Discovery for AD/ADRD and Beyond workshop

The National Institute on Aging (NIA) is sponsoring the Agentic AI and Robotics: Accelerating Discovery for AD/ADRD and Beyond workshop, to be held virtually on August 27, 2026, 2:00 - 6:00 PM EDT. 

This workshop convenes leading experts from academia and industry to explore how agentic AI and robotics are transforming biomedical research by accelerating the… read more

ISTAART Intermissions 2026 graphic promoting Alzheimer Disease Sequencing Project (ADSP) And The ADSP Phenotype Harmonization Consortium (ADSP PHC): Data Access, Use And Collaboration session
ADSP and ADSP-PHC are hosting an ISTAART Intermissions Networking Session

The Alzheimer's Disease Sequencing Project (ADSP) and the ADSP Phenotype Harmonization Consortium (PHC) will be hosting an ISTAART Intermissions networking session at AAIC 2026 on Monday, July 13, from 12:15 - 2:00pm. The objective of this session is to engage researchers at any level who are interested in accessing and performing research using ADSP data. This… read more

ADSP PHC logo
ADSP Phenotype Harmonization Consortium Release 4 is Out!

The fourth release from the Alzheimer’s Disease Sequencing Project Phenotype Harmonization Consortium (ADSP-PHC), which includes harmonized phenotypes for ADSP participants with sequencing, is available in the ADSP Umbrella Dataset (NG00067v20). Importantly, this release includes harmonized diagnosis and plasma biomarkers for the first time. Existing users with… read more

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New ADSP Umbrella data release - NG00067

This dataset includes sequencing data and harmonized phenotypes from cohorts sequenced by the Alzheimer’s Disease Sequencing Project and other AD and Related Dementia’s studies. Samples are processed using a common workflow called VCPA (Variant Calling Pipeline and data management tool), a functionally equivalent CCDG/TOPMed pipeline.