The Alzheimer’s Disease Sequencing Project (ADSP) is performing cutting edge analyses of genome sequencing and related health data across global populations to understand the genetic architecture of Alzheimer’s Disease and Related Dementias.

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For ADSP Members

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For Researchers

Learn more ADSP research, data, and resources, and ways to get involved.

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For the Public

(Coming soon!) See how ADSP is helping to shape the science of Alzheimer’s Disease research.

News and Publications

ISTAART Intermissions 2026 graphic promoting Alzheimer Disease Sequencing Project (ADSP) And The ADSP Phenotype Harmonization Consortium (ADSP PHC): Data Access, Use And Collaboration session
ADSP and ADSP-PHC are hosting an ISTAART Intermissions Networking Session

The Alzheimer's Disease Sequencing Project (ADSP) and the ADSP Phenotype Harmonization Consortium (PHC) will be hosting an ISTAART Intermissions networking session at AAIC 2026 on Monday, July 13, from 12:15 - 2:00pm. The objective of this session is to engage researchers at any level who are interested in accessing and performing research using ADSP data. This networking session, led by Drs. DeStefano, Hohman, and Wang, will provide the opportunity for AAIC attendees currently using or interested in using ADSP data to connect, address data challenges, and build new collaborations. This session will provide opportunities to educate the research community about the available ADSP data, to answer specific questions about ADSP data and resources, and to enhance connections and collaborations among ADSP data users. The expected outcome is broader awareness of the ADSP resources, new ADSP data users, and new potential collaborations, all leading to more impactful research in the field of ADRD genomics.



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Colorful image of multiple open journals. Image by kconcha from Pixabay.
Recent publications
Okorie M, et al. Cross-ancestry polygenic risk scores enhance Alzheimer's disease risk prediction in multiethnic cohorts.   Alzheimer's & dementia: the journal of the Alzheimer's Association.  

Peloso GM, et al. Whole genome sequencing analysis of over 3500 individuals dementia-free over 85 years old.   Journal of Alzheimer's disease : JAD.  

Nafikov RA, et al. Variant Prioritization by Pedigree-Based Haplotyping.   Genetic epidemiology.  


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