The Alzheimer’s Disease Sequencing Project (ADSP) is performing cutting edge analyses of genome sequencing and related health data across global populations to understand the genetic architecture of Alzheimer’s Disease and Related Dementias.

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For ADSP Members

Visit your customized dashboard to view your ADSP information.

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For Researchers

(Coming soon!) Learn more ADSP research, data, and resources, and ways to get involved.

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For the Public

(Coming soon!) See how ADSP is helping to shape the science of Alzheimer’s Disease research.

News and Publications

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New ADSP Umbrella data release - NG00067

This dataset includes sequencing data and harmonized phenotypes from cohorts sequenced by the Alzheimer’s Disease Sequencing Project and other AD and Related Dementia’s studies. Samples are processed using a common workflow called VCPA (Variant Calling Pipeline and data management tool), a functionally equivalent CCDG/TOPMed pipeline.



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Colorful image of multiple open journals. Image by kconcha from Pixabay.
Recent publications
Peloso GM, et al. Whole genome sequencing analysis of over 3500 individuals dementia-free over 85 years old.   Journal of Alzheimer's disease : JAD.  

Nafikov RA, et al. Variant Prioritization by Pedigree-Based Haplotyping.   Genetic epidemiology.  

Temple SD, et al. Multiple-testing corrections in case-control studies using identity-by-descent segments.   American journal of human genetics.  


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