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Application of the STAAR Framework in Detecting Rare Variant Associations with Alzheimer's Disease and Related Dementias: Insights and Implications

Presentation or Session Status
Poster presentation
Authors
Dongyu Wang1, Sabrina Abbruzzese1, Nancy Heard-Costa2,3, Andy Rampersaud4, Eden Martin5,6,7, Adam Naj8, Bilcag Akgun5,7, Brian Kunkle5,6,7, Sudha Seshadri2,3,9, Gina Peloso1, The Alzheimer's Disease Sequencing Project, Anita L. DeStefano1, Zilin Li10, Xihao Li11,12, Seung Hoan Choi1

Affiliations
1. Department of Biostatistics, Boston University School of Public Health, Boston, MA, 02118, USA.
2. Department of Neurology, Boston University Chobanian & Avedisian School of Medicine, Boston, MA, 02118, USA.
3. NHLBI Framingham Heart Study, Framingham, MA, 01702, USA.
4. Research Computing Services, Information Services & Technology, Boston University, Boston, MA, 02215, USA.
5. John P Hussman Institute for Human Genomics, Miami, FL 33136, USA.
6. John T Macdonald Department of Human Genetics, Miami, FL 33136, USA.
7. University of Miami Miller School of Medicine, Miami, FL 33136, USA.
8. Department of Biostatistics, Epidemiology, and Informatics, Department of Pathology and Laboratory Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA 19104, USA.
9. Glenn Biggs Institute for Alzheimer's Disease and Neurodegenerative Diseases, University of Texas Health San Antonio, San Antonio, TX, 78229, USA.
10. School of Mathematics and Statistics, Northeast Normal University, Changchun, Jilin 130024, China.
11. Department of Biostatistics, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.
12. Department of Genetics, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.