Skip to main content

APOL1 haplotype analysis and channel flux assays suggest the M1 protective signal reflects the KIK haplotype, not p.N264K alone

Abstract or Session
Presentation or Session Status
Poster presentation
October 23, 2026
Authors
Diya Yang (Cleveland Institute for Computational Biology; Department of Population and Quantitative Health Sciences, School of Medicine, Case Western Reserve University, Cleveland, OH, USA), Shiying Liu (Cleveland Institute for Computational Biology; Department of Population and Quantitative Health Sciences, School of Medicine, Case Western Reserve University, Cleveland, OH, USA), Korey R. Bartolomeo (Cleveland Clinic, Department of Heart, Blood and Kidney Research, Cleveland, OH, USA), Agustin Gonzalez-Vicente (Department of Physiology and Biophysics, School of Medicine, Case Western Reserve University, Cleveland, OH, USA), Scott M. Williams (Department of Population and Quantitative Health Sciences; Department of Genetics and Genome Sciences, School of Medicine, Case Western Reserve University, Cleveland, OH, USA), Jonathan L. Haines (Cleveland Institute for Computational Biology; Department of Population and Quantitative Health Sciences; Department of Genetics and Genome Sciences, School of Medicine, Case Western Reserve University, Cleveland, OH, USA), Dana C. Crawford (Cleveland Institute for Computational Biology; Department of Population and Quantitative Health Sciences, School of Medicine, Case Western Reserve University, Cleveland, OH, USA), William S. Bush (Cleveland Institute for Computational Biology; Department of Population and Quantitative Health Sciences; Department of Genetics and Genome Sciences, School of Medicine, Case Western Reserve University, Cleveland, OH, USA), John F. O'Toole (Cleveland Institute for Computational Biology, Case Western Reserve University; Cleveland Clinic, Department of Heart, Blood and Kidney Research, Cleveland, OH, USA), John R. Sedor (Cleveland Institute for Computational Biology; Department of Physiology and Biophysics, School of Medicine, Case Western Reserve University; Cleveland Clinic, Department of Heart, Blood and Kidney Research, Cleveland, OH, USA)
Program Number/Abstract ID
Board 8368F