Presentation or Session Status
Poster presentation
July 28, 2025
Authors
Alexandra N. Regelson1,2; Derek Archer1,2; Alaina Durant1,2; Subhabrata Mukherjee3; Michael L. Lee3; Seo-Eun Choi3; Phoebe Scollard3; Emily H. Trittschuh4,5; Jesse Mez6; William S. Bush7; Amanda B. Kuzma8; The Alzheimer's Disease Neuroimaging Initiative (ADNI); The Alzheimer's Disease Sequencing Project (ADSP); Michael L. Cuccaro9; Carlos Cruchaga10,11; Lindsay A. Farrer6,12,13; Li-San Wang8; Gerard D. Schellenberg8; Richard P. Mayeux14,15,16; Walter A. Kukull17; C. Dirk Keene18; Andrew J. Saykin19,20; Sterling C. Johnson21; Corinne D. Engelman21; David A. Bennett22; Lisa L. Barnes22; Eric B. Larson3; Kwangsik Nho23; Alison M. Goate24; Alan Renton25, Edoardo Marcora24, Brian Fulton-Howard24, Tulsi Patel25, Shannon L Risacher19; Anita DeStefano12, Julie A. Schneider22; Mohamad Habes25; Sudha Seshadri25; Claudia Satizabal25; Pauline Maillard26; Arthur W. Toga27; Karen Crawford27; Duygu Tosun28; Jeffery Vance9; Elizabeth C. Mormino29; Charles DeCarli29; Thomas J. Montine31; Gary W. Beecham32; Sarah Biber33; Philip L. De Jager34,35; Vilas Menon35; Annie J. Lee3; Adam M. Brickman15,36,37; Badri Vardarajan35; Christiane Reitz36; Jennifer J. Manly15,36,37; Jason Fletcher38; Miguel Arce Renteria34; Jason Song39; Qiongshi Lu39,40; Paul K. Crane3; Timothy J. Hohman1,2; Logan Dumitrescu1,2
Author Affiliations:
1Vanderbilt Memory & Alzheimer's Center, Vanderbilt University Medical Center, Nashville, TN, 37212, USA
2Vanderbilt Genetics Institute, Vanderbilt University Medical Center, Nashville, TN, 37232, USA
3Department of Medicine, University of Washington, Seattle, WA, 98195, USA
4Department of Psychiatry and Behavioral Sciences, University of Washington School of Medicine, Seattle, WA, 98195, USA
5VA Puget Sound Health Care System, GRECC, Seattle, WA, 98108, USA
6Department of Neurology, Boston University Chobanian & Avedisian School of Medicine, Boston, MA, 02118, USA
7Cleveland Institute for Computational Biology, Department of Population and Quantitative Health Sciences, Case Western Reserve University, Cleveland, OH, 44106, USA
8Penn Neurodegeneration Genomics Center, Department of Pathology and Laboratory Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, 19104, USA
9John P. Hussman Institute for Human Genomics, University of Miami Miller School of Medicine, Miami, FL, 33136, USA
10Department of Psychiatry, Washington University School of Medicine, St. Louis, MO, 63110, USA
11NeuroGenomics and Informatics Center, Washington University School of Medicine, St. Louis, MO, 63108, USA
12Department of Biostatistics, Boston University School of Public Health, Boston, MA, 02118, USA
13Department of Medicine (Biomedical Genetics), Boston University Chobanian & Avedisian School of Medicine, Boston, MA, 02118, USA
14Columbia University, New York, NY, 10034, USA
15The Taub Institute for Research on Alzheimer's Disease and the Aging Brain, Columbia University, New York, NY, 10032, USA
16The Institute for Genomic Medicine, Columbia University Medical Center and The New York Presbyterian Hospital, New York, NY, 10032, USA
17Department of Epidemiology, School of Public Health, University of Washington, Seattle, WA, 98195, USA
18Department of Laboratory Medicine and Pathology, University of Washington, Seattle, WA, 98195, USA
19Department of Radiology and Imaging Services, Indiana University School of Medicine, Indianapolis, IN, 46202, USA
20Department of Medical and Molecular Genetics, School of Medicine, Indiana University, Indianapolis, IN, 46202, USA
21Wisconsin Alzheimer's Disease Research Center, University of Wisconsin School of Medicine and Public Health, Madison, WI, 53792, USA;
22Rush Alzheimer's Disease Center, Rush University Medical Center, Chicago, IL, 60612, USA
23Indiana Alzheimer's Disease Research Center, Indiana University School of Medicine, Indianapolis, IN, 46202, USA
24Ronald M Loeb Center for Alzheimer's Disease, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA
25Glenn Biggs Institute for Alzheimer's & Neurodegenerative Diseases, University of Texas Health Science Center at San Antonio, San Antonia, TX, USA
26Department of Neurology and Center for Neuroscience, University of California, Davis, Davis, CA, 95616, USA
27University of Southern California Stevens Neuroimaging and Informatics Institute, Keck School of Medicine, University of Southern California, Los Angeles, CA, 90063, USA
28Department of Radiology, University of California, San Francisco, San Francisco, CA, 94143, CA, USA
29Department of Neurology and Neurological Sciences, Stanford University School of Medicine, Stanford, CA, 94305, USA
30Department of Neurology & Imaging of Dementia and Aging Laboratory, University of California Davis, Sacramento, CA, 95817, USA
31Department of Pathology, Stanford University School of Medicine, Stanford, CA, 94305, USA
32John T MacDonald Foundation Department of Human Genetics, University of Miami Miller School of Medicine, Miami, FL, 33136, USA
33National Alzheimer's Coordinating Center, University of Washington, Seattle, WA, 98195, USA
34Department of Neurology, Columbia University Medical Center, New York, NY, 10034, USA
35Center for Translational and Computational Neuroimmunology, Columbia University Medical Center, New York, NY, 10034, USA
36G.H. Sergievsky Center, Vagelos College of Physicians and Surgeons, Columbia University, New York, NY, 10032, USA
37Department of Neurology, Vagelos College of Physicians and Surgeons, Columbia University, and the New York Presbyterian Hospital, New York, NY, 10032, USA
38La Follette School of Public Affairs, University of Wisconsin-Madison, Madison, WI, 53706, USA
39Department of Statistics, University of Wisconsin-Madison, Madison, WI, 53706, USA
40Department of Biostatistics and Medical Informatics, University of Wisconsin-Madison, Madison, 53706, WI, USA
Author Affiliations:
1Vanderbilt Memory & Alzheimer's Center, Vanderbilt University Medical Center, Nashville, TN, 37212, USA
2Vanderbilt Genetics Institute, Vanderbilt University Medical Center, Nashville, TN, 37232, USA
3Department of Medicine, University of Washington, Seattle, WA, 98195, USA
4Department of Psychiatry and Behavioral Sciences, University of Washington School of Medicine, Seattle, WA, 98195, USA
5VA Puget Sound Health Care System, GRECC, Seattle, WA, 98108, USA
6Department of Neurology, Boston University Chobanian & Avedisian School of Medicine, Boston, MA, 02118, USA
7Cleveland Institute for Computational Biology, Department of Population and Quantitative Health Sciences, Case Western Reserve University, Cleveland, OH, 44106, USA
8Penn Neurodegeneration Genomics Center, Department of Pathology and Laboratory Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, 19104, USA
9John P. Hussman Institute for Human Genomics, University of Miami Miller School of Medicine, Miami, FL, 33136, USA
10Department of Psychiatry, Washington University School of Medicine, St. Louis, MO, 63110, USA
11NeuroGenomics and Informatics Center, Washington University School of Medicine, St. Louis, MO, 63108, USA
12Department of Biostatistics, Boston University School of Public Health, Boston, MA, 02118, USA
13Department of Medicine (Biomedical Genetics), Boston University Chobanian & Avedisian School of Medicine, Boston, MA, 02118, USA
14Columbia University, New York, NY, 10034, USA
15The Taub Institute for Research on Alzheimer's Disease and the Aging Brain, Columbia University, New York, NY, 10032, USA
16The Institute for Genomic Medicine, Columbia University Medical Center and The New York Presbyterian Hospital, New York, NY, 10032, USA
17Department of Epidemiology, School of Public Health, University of Washington, Seattle, WA, 98195, USA
18Department of Laboratory Medicine and Pathology, University of Washington, Seattle, WA, 98195, USA
19Department of Radiology and Imaging Services, Indiana University School of Medicine, Indianapolis, IN, 46202, USA
20Department of Medical and Molecular Genetics, School of Medicine, Indiana University, Indianapolis, IN, 46202, USA
21Wisconsin Alzheimer's Disease Research Center, University of Wisconsin School of Medicine and Public Health, Madison, WI, 53792, USA;
22Rush Alzheimer's Disease Center, Rush University Medical Center, Chicago, IL, 60612, USA
23Indiana Alzheimer's Disease Research Center, Indiana University School of Medicine, Indianapolis, IN, 46202, USA
24Ronald M Loeb Center for Alzheimer's Disease, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA
25Glenn Biggs Institute for Alzheimer's & Neurodegenerative Diseases, University of Texas Health Science Center at San Antonio, San Antonia, TX, USA
26Department of Neurology and Center for Neuroscience, University of California, Davis, Davis, CA, 95616, USA
27University of Southern California Stevens Neuroimaging and Informatics Institute, Keck School of Medicine, University of Southern California, Los Angeles, CA, 90063, USA
28Department of Radiology, University of California, San Francisco, San Francisco, CA, 94143, CA, USA
29Department of Neurology and Neurological Sciences, Stanford University School of Medicine, Stanford, CA, 94305, USA
30Department of Neurology & Imaging of Dementia and Aging Laboratory, University of California Davis, Sacramento, CA, 95817, USA
31Department of Pathology, Stanford University School of Medicine, Stanford, CA, 94305, USA
32John T MacDonald Foundation Department of Human Genetics, University of Miami Miller School of Medicine, Miami, FL, 33136, USA
33National Alzheimer's Coordinating Center, University of Washington, Seattle, WA, 98195, USA
34Department of Neurology, Columbia University Medical Center, New York, NY, 10034, USA
35Center for Translational and Computational Neuroimmunology, Columbia University Medical Center, New York, NY, 10034, USA
36G.H. Sergievsky Center, Vagelos College of Physicians and Surgeons, Columbia University, New York, NY, 10032, USA
37Department of Neurology, Vagelos College of Physicians and Surgeons, Columbia University, and the New York Presbyterian Hospital, New York, NY, 10032, USA
38La Follette School of Public Affairs, University of Wisconsin-Madison, Madison, WI, 53706, USA
39Department of Statistics, University of Wisconsin-Madison, Madison, WI, 53706, USA
40Department of Biostatistics and Medical Informatics, University of Wisconsin-Madison, Madison, 53706, WI, USA