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Accepted

Revealing ancestry-specific genetic effects on Alzheimer Disease in African Americans

Presentation or Session Status
Poster presentation
November 7, 2024
Authors
Kara L. Hamilton-Nelson1, Farid Rajabli1,2, Kyle Scott1, Giuseppe Tosto3, Scott M. Williams4, Brian Kunkle1,2, Jeffery M. Vance1,2,5, Michael Cuccaro1,2, Christiane Reitz3, Susan Blanton1,2, Katalina McInerney5, Jonathan L. Haines4, Goldie Byrd6, ADGC, Margaret A. Pericak-Vance1,2,5

(1) John P. Hussman Institute for Human Genomics, University of Miami Miller School of Medicine, Miami, FL, USA,
(2) Dr. John T. Macdonald Foundation Department of Human Genetics, University of Miami Miller School of Medicine, Miami, FL, USA
(3) Taub Institute for Research on Alzheimer's Disease and the Aging Brain, Department of Neurology, Columbia University College of Physicians and Surgeons
(4) Department of Population and Quantitative Health Sciences, Case Western Reserve University School of Medicine
(5) Department of Neurology, University of Miami Miller School of Medicine, Miami, FL, USA
(6) Maya Angelou Center for Health Equity, Wake Forest University, Winston-Salem, NC, USA

The genetic architecture of limbic white matter microstructure in aging

Presentation or Session Status
Poster presentation
Authors
Anna Lorenz, Aditi Sathe, Dimitrios Zaras, Yisu Yang, Alaina Durant, Michael E. Kim, Chenyu Gao, Nancy R. Newlin, Karthik Ramadass, Praitayini Kanakaraj, Nazirah Mohd Khairi, Zhiyuan Li, Tianyuan Yao, Yuankai Huo, Logan Dumitrescu, Niranjana Shashikumar, Kimberly R. Pechman, T. Bryan Jackson, Abigail W. Workmeister, Shannon L. Risacher, Lori L. Beason-Held, Yang An, Konstantinos Arfanakis, Guray Erus, Christos Davatzikos, Mohamad Habes, Di Wang, Duygu Tosun, Arthur W. Toga, Paul M. Thompson, Elizabeth C. Mormino, Panpan Zhang, Kurt Schilling, Alzheimer's Disease Neuroimaging Initiative (ADNI), The BIOCARD Study Team, The Alzheimer's Disease Sequencing Project (ADSP), Marilyn Albert, Walter Kukull, Sarah A. Biber, Bennett A. Landman, Sterling C. Johnson, Barbara Bendlin, Julie Schneider, Lisa L. Barnes, David A. Bennett, Angela L. Jefferson, Susan M. Resnick, Andrew J. Saykin, Timothy J. Hohman, Derek B. Archer

Genetic Predictors that Modify the Association Between Hippocampal Volume and Memory Performance

Presentation or Session Status
Poster presentation
November 8, 2024
Authors
Abel Belachew1, Sarah Biber3, Walter Kukull3, Shubhabrata Mukherjee3, Paul Crane3, Jesse B. Mez4, Seo-Eun Choi3, Brandon Klinedinst3, Michael L. Lee3, Phoebe Scollard3, Shannon Risacher5, Meichen Yu5, Christos Davatzikos6, Haochang Shou6, Guray Erus6 , Yuhan Cui6, Adam Naj6, Li-San Wang6, Jonathan Haines7, Margaret Pericak-Vance8, Richard Mayeux9, Alaina Durant1, Alexandra Regelson1, Ting-Chen Wang1, Derek Archer1,2, Logan Dumitrescu1,2, and Timothy J. Hohman1,2

1Vanderbilt Memory and Alzheimer’s Center, Vanderbilt University Medical Center, Nashville, TN, USA; 2Vanderbilt Genetics Institute, Vanderbilt University Medical Center, Nashville, TN, USA; 3Department of Medicine, University of Washington, Seattle, WA, USA, 4Department of Neurology, Boston University School of Medicine, Boston, MA, USA; 5School of Medicine, Indiana University, Indianapolis, IN, USA; 6Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA; 7School of Medicine, Case Western Reserve University, Cleveland, OH, USA; 8Miller School of Medicine, University of Miami, Coral Gables, FL, USA; 9Department of Neurology, Columbia University, New York, NY, USA

From query to visualization: programmatic access and interactive workspaces for Alzheimer's disease genetics and >100,000 omics datasets

Presentation or Session Status
Poster presentation
November 6, 2024
Authors
Emily Greenfest-Allen12, Jeffrey Cifello12, Pavel P. Kuksa123, Sam Tate12, Luke Carter12, Otto Valladares123, Wan-Ping Lee123, Yuk Yee Leung123, Li-San Wang123

1 Penn Neurodegeneration Genomics Center, Department of Pathology and Laboratory Medicine, 2 Institute for Biomedical Informatics, 3 Institute on Aging, Perelman School of Medicine, University of Pennsylvania

NIA Genetics of Alzheimer's Disease Data Storage Site (NIAGADS): 2024 Update

Presentation or Session Status
Poster presentation
November 6, 2024
Authors
Joseph Manuel12, Amanda Kuzma12, Otto Valladares12, Heather Nicaretta12, Prabhakaran Gangadharan12, Zivadin Katanic12, Maureen Kirsch12, Youli Ren12, Lauren Bass12, Naveensri Saravanan12, Jascha Brettschneider12, Andrew Wilk12, Yi Zhao12, Liming Qu12, Michelle K Moon12, Alexis Lerro Rose12, Peter Keskinen12, Jeffrey Cifello12, Wenhwai Horng12, Sam Tate12, Flawless Robbins12, Heather White12, Luke Carter12, Shin-Yi Chou6, Adam Naj15, Emily Greenfest-Allen12, Pavel Kuksa12, Yuk Yee Leung123, Wan-Ping Lee12, Gerard D. Schellenberg13, Li-San Wang123

1 Penn Neurodegeneration Genomics Center, Department of Pathology and Laboratory Medicine, 2 Institute for Biomedical Informatics, 3 Institute on Aging, 5 Department of Epidemiology, University of Pennsylvania Perelman School of Medicine, 6 Department of Economics, Lehigh University

Harmonizing 60,000 whole genome sequence data to advance Alzheimer's Disease genetics research - joint effort by the Alzheimer's Disease Sequencing Project and the Genome Center for Alzheimer's Disease

Presentation or Session Status
Poster presentation
November 6, 2024
Authors
Prabhakaran Gangadharan, Wan-Ping Lee, Amanda B Kuzma, Heather Nicaretta, Liming Qu, Luke Carter, Youli Ren, Laura Cantwell, Otto Valladares, Yi Zhao, Taha Iqbal, Mike Schmidt, Pedro Mena, Alzheimer's Disease Sequencing Project, Clifton Dalgard, Brian Kunkle, Will Bush, Eden Martin, Adam Naj, Jonathan L. Haines, Margaret A. Pericak-Vance, Li-San Wang, Gerard D. Schellenberg, Yuk Yee Leung

Copy Number Variation and Haplotype Analysis of 17q21.31 Reveals Increased Risk Associated with Progressive Supranuclear Palsy and Gene Expression Changes

Presentation or Session Status
Poster presentation
November 6, 2024
Authors
Hui Wang, PhD, Timothy S Chang, MD PhD, Beth A. Dombroski, PhD, Po-Liang Chen, PhD, Ya-Qin Si, Albert Tucci, Chong Li, Li-San Wang, PhD, Jung-Ying Tzeng, PhD, Daniel H Geschwind, MD PhD, Gerard Schellenberg, PhD, Wan-Ping Lee, PhD